This is the ultimate buyer’s guide to the Best Msm Powders. We’ve listed our top picks, including the Most popular, Top-rated, and Bestselling Products.
After hours of scanning and analyzing the market, using too many factors, we have found the Best Msm Powders of 2022. Check out our ranking below!

Top 20 Best Msm Powders of 2022

Best Msm Powders 2022 (Reviews)

Doctor's Best MSM Powder with OptiMSM, Non-GMO, Vegan, Gluten Free, Soy Free, 250 Grams

 in stock
10 new from $8.99
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as of February 26, 2022 9:11 pm


  • DOCTOR’S BEST MSM FEATURES OPTIMSM - with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy.MSM is a natural sulfur compound that helps support the formation of healthy connective tissues. It also helps support overall joint mobility, and a normal range of motion. It also may help reduce oxidative damage to support a immune system
  • BENEFITS TO JOINTS: MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion.*
  • IMMUNE SUPPORT: MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response.*
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.*
  • CLINICAL STUDIES: Sulfur continues to be an important dietary nutrient to support healthy aging. With its regulation of glutathione and other ways in the body, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.

NOW Supplements, MSM (Methylsulfonylmethane) Powder, Supports Healthy Cartilage*, Joint Health*, 1-Pound

$12.76  in stock
16 new from $12.76
Free shipping
as of February 26, 2022 9:11 pm


  • JOINT SULFUR FOR CONNECTIVE TISSUE*: MSM, in its role in the body's sulfur cycle, helps to create the chemical links needed to form and maintain numerous different types of structural tissues of the human body, including connective tissues, such as articular cartilage and skin.*
  • POWDER/SUPPORTS HEALTHY CARTILAGE*: Sulfur compounds are found in all body cells and are indispensable for life.*
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Dairy Free, Egg Free, Made without Gluten, Corn Free, Soy Free, Kosher, Vegan/Vegetarian, Sugar Free, Nut Free
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968

Kala Health MSMPure Fine Powder, 8.8 oz, Fast Dissolving Organic Sulfur Crystals, 99% Pure Distilled MSM Supplement, Made in USA

$12.95  in stock
2 new from $12.95
Free shipping
as of February 26, 2022 9:11 pm


  • WHY MSMPure POWDER? We only use Optimsm which is “the purest MSM on the Planet". Our MSM is the organic form of naturally occurring Sulfur. MSMPure goes through a propriety multi-stage distillation process that ensures a 99.9% pure, third party tested to meet our stringent product specifications. This is the only GRAS-designated, Kosher & Halal certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM backed by extensive toxicology data.
  • WHAT ARE MSMPure BENEFITS TO JOINTS? Improves joint function and mobility, Reduces joint pain and stiffness, Increases range of motion, Protects cartilage, Decreases swelling and inflammation, Aids in short term recovery by reducing inflammatory responses and swelling involved in joint pain and fatigue.
  • MSMPure IS COMMONLY USED NATURALLY FOR MEN AND WOMEN WITH: shoulder, hands, fingers, wrist, ankles, heel, knees, hip, lumbar back, lower back or foot inflammation
  • MSMPure ADDITIONAL BENEFITS: Known as "Nature's Beauty Mineral" for faster hair growth, promote nail growth, improve skin texture, younger looking skin, may reduce fine lines and wrinkles, restores collagen production and acne improvement. Immune Support: Sulfur, an active component of MSMPure, supports restorative balance for the immune system
  • The MSMPure GUARANTEE: No-Risk 100% Satisfaction Guarantee if you for any reason do not feel MSM is helping you. At Kala Health we stand behind every product we manufacture for our customers. MSM Powder (Methylsulfonylmethane) - MSM Powder - Hair Powder - Sulfur Powder - MSM Supplement - MSM Crystals - Bulk Powders MSM Powder (1 Kilogram - 2.2 lbs)

$23.96  in stock
2 new from $23.96
Free shipping
as of February 26, 2022 9:11 pm


  • Joint Support - MSM supplement, or MSM pure powder, may support joint function.* It may have an anti-inflammatory effect, and is also thought to play an important role in making collagen, which is vital for the joints.*
  • Fortifies Immune Function* - Pure MSM supplement is believed to have anti-inflammatory compounds, which has been used to support the immune system.* MSM Powder, or MSM granules, is a natural immune system supplement.*
  • Promotes Healthy Skin And Hair* - Using MSM for hair support may provide sulfur, which is thought to restore collagen production that supports the skin and is a building block of keratin, an essential protein for promoting the skin and hair, MSM hair growth supplement.*
  • Aids Digestion* - Used widely to assist in removing metabolic waste from cells and rebuild the lining of the digestive tract. This MSM supplement, also sulfur powder for plants, may support certain reactions to specific foods.*
  • MSM For Horses - MSM has been used to support joint mobility, connective tissue, hair, hide and hooves of horses.* Consult your veterinarian before giving it to pets.*

Nutricost Pure MSM Powder 500 Grams (Methylsulfonylmethane)

$13.95  in stock
2 new from $13.95
Free shipping
as of February 26, 2022 9:11 pm


  • 1 Gram of MSM Powder Per Serving (500 Servings)
  • High Quality MSM Powder
  • 500 Grams of Lab Tested Pure MSM Powder Per Bottle
  • Gluten Free and Non-GMO
  • Manufactured In a GMP Compliant, FDA Registered Facility

Methylsulfonylmethane MSM Powder (2 lbs), 100% Pure, Joint & Connective Tissue Health, Respiratory & Digestive Support*

$22.99  in stock
as of February 26, 2022 9:11 pm


  • PURE MSM Powder provides a pure undiluted supplement
  • A naturally derived sulfur found in fruits, vegetables, and milk
  • 100% Pure: Never any additives or fillers
  • Quick-dissolving for water or citrus juice mixtures
  • Made in Utah, USA

Micro Ingredients Pure MSM Powder (Methysulfonylmethane), 1 Kg (1 Year Supply), Filler Free, Pure MSM Supplement, Bioavailable Source of Organic Sulfur, Joint Health Support, Vegan and Pet Friendly

$21.95  in stock
as of February 26, 2022 9:11 pm


  • Micro Ingredients Pure MSM Powder, 1000 Grams (2.2 Pounds and 1 Year Supply), Filler Free, Vegan, Non-GMO and Pet Friendly.
  • A Bioavailable Source of Sulfur, with Antioxidant and Protein-Building Functions.
  • No Additives, No Preservatives, No Fillers, No GMOs, No Artificial Colors, No Flavor, No Soy and No Gluten.
  • Scoop included to get the measurement every time. Take it daily with or between meals by adding it to a shake or smoothie, and see what the most nutrient dense food on the planet is all about.
  • Powder lover? Take it naturally in powder for higher concentration, quicker absorption, easier on the stomach, and more ways to have fun!

Lifetime 100% Pure MSM (Methylsulfonylmethane) Powder | Supports Healthy Joints & Skin | 2500 mg Per Serving | 16 oz, 180 Servings

$20.99  in stock
6 new from $20.99
Free shipping
as of February 26, 2022 9:11 pm


  • What Is Msm: MSM is a sulfur containing compound that may help to maintain optimal joint health
  • Healthy Skin: Sulfur is used in the production of collagen, a key component of healthy skin
  • Healthy Joints: Sulfur helps cells clear excess fluids that can cause uncomfortable joints
  • Powerful: Made w/ quality and potency; 2,500mg of 100% Pure MSM in every serving

Kala Health MSMPure Coarse Powder Flakes, Organic Sulfur Crystals, 99.9% Pure Distilled MSM Supplement, Made in The USA, 1lb

$22.95  in stock
as of February 26, 2022 9:11 pm


  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

Sulfur Defense 99.9% Pure MSM Powder Made in The USA - Organic Methylsulfonylmethane Crystals - Vegan, Non-GMO, Gluten-Free - Immune System Booster, Soothes Joint Pain, Younger Skin, Hair, and Nails

$27.95  in stock
2 new from $27.95
Free shipping
as of February 26, 2022 9:11 pm


  • 99.9% PURE - Sulfur Defense MSM or methylsulfonylmethane supplements go through a multi-stage distillation process that filters out all impurities. Sulfur Defense is made in the USA, tested, and approved under the highest standards.
  • BUILD YOUR BODY'S DEFENSE - Sulfur Defense MSM is a compound that aids other essential nutrients to be absorbed faster by your cells - and serves as a foundation for building your body's natural defense against harmful elements in your environment.
  • TOTAL BODY SUPPORT - Immunity booster, antioxidant, helps in faster cell regeneration, and helps soothe aching joints. Feel the difference in your body when you start taking Sulfur Defense, and in as fast as 1 week.
  • LOOK & FEEL YOUNGER EVERYDAY - Notice yourself with a more youthful appearance, reduced fine lines and wrinkles, glowing skin, with stronger hair and nails. Sulfur Defense will transform your body from head to toe, and from the inside out.
  • SAFE FOR ALL - Vegan, non-GMO, Gluten-Free, Allergen-Free, Kosher, and Halal. Sulfur Defense MSM is backed by extensive research to ensure no discomfort, no harmful side effects, and beneficial to everyone, even those with dietary restrictions.

Methylsulfonylmethane MSM Powder (1 lb, ½ TSP per Serving), 100% Pure, May Support Joint & Connective Tissue Health, Respiratory & Digestive System Support*

$14.99  in stock
as of February 26, 2022 9:11 pm



Gold Standard Organic Sulfur Crystals 1lb - 99.9% Pure MSM Crystals - Largest Granular Flakes Available - 3rd Party Tested

$39.99  in stock
as of February 26, 2022 9:11 pm


  • Quality and Purity: The Only Recommended Organosulfur Supplement by Independent Researchers. 99.9% Pure, Therapeutic-Grade Methylsulfonylmethane.
  • Value: Provides far more absorption power and effect than other crystals and 500-2000% more MSM than most pills, powder, or capsules.
  • Gold Standard: This is the original MSM in a gold bag, the original and Only Large Crystal Organic Sulfur - 99.9% Pure MSM.
  • The Gold Standard difference is the large size of our crystals and the unmatched absorption and potency. No other product matches in quality, size, purity, and absorption.
  • Top Notch Manufacturing: We start with Quality American Ingredients, not dirty petro chemicals. Double Distilled for Maximum Purity. We use low heat because overheating diminishes effectiveness. With our crystals, you get no fillers. No anti-caking additives. No binders. Our crystals are manufactured just for us in a facility with high oversight, hands-on, quality control.

Jarrow Formulas MSM - 2.2 lbs Powder - Methylsulfonylmethane - Important Source of Organic Sulfur - Antioxidant, Supports Joints - Approx. 1000 Servings

$27.57  in stock
2 new from $27.57
Free shipping
as of February 26, 2022 9:11 pm


  • Important Source of Organic Sulfur: Jarrow Formulas MSM is an organic source of bioavailable sulfur; It provides the highest quality of MSM available, supporting amino acids and proteins in cartilage; This formula supports joint health
  • Sulfur Highlights: Sulfur is an antioxidant mineral found in the body’s structural proteins (i.e., chondroitin sulfate, dermatan sulfate and hyaluronic acid); Sulfur-containing structural proteins are in connective tissues like joint cartilage and skin
  • For Best Results: For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon
  • Superior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency

Pure Encapsulations - MSM Powder - Hypoallergenic Supplement Supports Joint, Immune, and Respiratory Health - 8 Ounces

$33.20  in stock
as of February 26, 2022 9:11 pm


  • Joint Health: MSM is a naturally-derived sulfur formula that helps support joint functionality and comfort, specifically connective tissue health.*
  • Immune Function: MSM also provides potential support for immune and respiratory health.*
  • Hair, Skin, & Nails: Sulfur also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

OptiMSM – Pure Methylsulfonylmethane MSM Supplement Powder – Organic, Gluten Free, Non-GMO – Best MSM Sulfur Crystals/Powder for Kids and Adults – Hair Growth, Inflammation, Skin Health

$22.95  in stock
as of February 26, 2022 9:11 pm


  • [Potent Full-Body Anti-Inflammatory] – MSM is the swiss army knife of naturally-occurring anti-inflammatory compounds. It helps reduce inflammation, gastrointestinal problems, speeds hair and nail growth, reverses the signs of aging, & so much more!
  • [OptiMSM Sets The Bar For Quality] – Kala Health brings you incredibly purity. Our Methylsulfonylmethane is distilled 4 separate times, removing all heavy metals, contaminants, and impurities. 1 pound of the finest sulfur crystals imaginable.
  • [Sensitivity-Conscious] – Everyone has sensitivities, but everyone can take OptiMSM. OptiMSM is 100% free from allergens such as yeast, sugar, starch, gluten, artificial flavors, colors, preservatives, chemicals, GMOs, BPA. 100% pure MSM ONLY!
  • [Made In The USA] – The industry has been flooded with poor quality MSM mass-produced and shipped internationally. OptMSM is proudly produced in the United States. Every batch is tested and certified for incomparable quality right here in the US.
  • [Perfect For Those You Love] – Try something different this year. Gift the ultimate present of good health and wellness. Surprise the person you love most in your life with the most beneficial Methylsulfonylmethane in the world. Gift OptiMSM today!

Emerald Labs MSM Powder 4,000 mg - Joint Support for Aches and Pains, Anti-Inflammatory, Stress Relief Support, Digestive System Support, Allergy Relief - 8 oz

$10.76  in stock
as of February 26, 2022 9:11 pm


  • Superior Joint Health: MSM is a naturally-derived sulfur formula that helps support joint functionality and comfort, specifically connective tissue health. MSM may also support flexibility and collagen production
  • Immune Support: MSM provides potential support for healthy immune function. MSM may support the lowering of inflammatory responses that contribute to swelling and stiffness, which supports the immune system and facilitates normal cellular activity
  • Strengthen Your Hair, Skin, and Nails: MSM (natural sulfur) also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails. Sulfur is required for the production of these "youthful" compounds
  • Natural Ingredients: Dietary supplement guaranteed to be free of corn, milk, soy, salt, sugar, wheat, yeast, artificial flavors or preservatives. Gluten Free. Additive-Free. No Magnesium Stearate. No Fillers. No Chemicals
  • The Emerald Labs Mission and Promise: Emerald Labs is committed to creating only clean, additive-free products. You can be 100 percent certain that our ingredients are offered to you in the purest form possible

Best Naturals 100% Pure MSM Powder, 1Lb

$11.99  in stock
2 new from $11.99
Free shipping
as of February 26, 2022 9:11 pm


  • 100% Pure Powder
  • Joint Support
  • For Connective Tissue & Health Cartilage
  • Supports Joint Function
  • All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency Guaranteed

500mg MSM Organic Sulfur Capsules by No Boundaries Health and Wellness – 180 Vegetable Capsules: No Excipients or Fillers – Premium Health Supplement: 99.9% Pure MSM Powder – Joints, Skin, Hair, Nail

 in stock
2 new from $19.99
Free shipping
as of February 26, 2022 9:11 pm


  • IMPROVES OVERALL HEALTH: MSM sulfur is essential to maintaining healthy skin and complexion, and can improve flexibility, hair and nail health, and detoxifies the body. If you’re looking to naturally increase your energy, relieve joint pain and improve your overall health, our organic sulfur powder pills may be the solution!
  • PURE, HIGH-QUALITY MSM: You can rest assured that No Boundaries Health and Wellness products are backed by honest scientific research and testing. Not only are our MSM crystal Capsules 99.9% pure, but they are also independently tested to ensure you receive the highest quality product.
  • INCREASE ANTIOXIDANT PRODUCTION: Sulfur and MSM powder is known to aid in the production of glutathione, an important antioxidant that helps protect cells from damage. Proper sulfur intake can also help stimulate connective tissue production that supports joints and combats joint pain and stiffness.

Hard Rhino MSM (Methylsulfonylmethane) Powder, 1 Kilogram (2.2 Lbs), Unflavored, Lab-Tested, Scoop Included

$25.49  in stock
as of February 26, 2022 9:11 pm


  • 1 Kilogram (2.2 Lbs), MSM (Methylsulfonylmethane) Powder with Scoop Included
  • Packaged in the USA.
  • In-House Lab Tested for Identity and Purity.
  • High Quality Ingredients at Value Prices.

Source Naturals MSM (Methylsulfonylmethane) Powder 16 Ounces(453.6 Grams)

$20.66  in stock
4 new from $20.66
as of February 26, 2022 9:11 pm


  • MSM is an organic sulfur-containing compound that’s used to improve immune function, lower inflammation and help restore healthy bodily tissue.
  • MSM provides biologically active sulfur, which is the fourth most plentiful mineral in the body and needed for many different critical bodily functions every single day.
  • A well-researched benefit of MSM is that it helps decrease joint inflammation, improves flexibility and restores collagen production.
  • MSM can help rebuild the lining of the digestive tract and lower inflammation/allergic reactions to certain foods.
  • MSM is necessary for collagen production, and collagen is what helps keep skin from becoming saggy, wrinkled, cracked and dry.

Best Msm Powders 2022 | Price Comparison

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5/5 - (377 votes)