This is the ultimate buyer’s guide to the Best Multi Strain Probiotics. We’ve listed our top picks, including the Most popular, Top-rated, and Bestselling Products.
After hours of scanning and analyzing the market, using too many factors, we have found the Best Multi Strain Probiotics of 2022. Check out our ranking below!


Top 20 Best Multi Strain Probiotics of 2022


18
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Best Multi Strain Probiotics 2022 (Reviews)


InnovixLabs Multi-Strain Probiotic Supplement - for Gut Health, 50 Billion CFU, Probiotics for Women, Probiotics for Men and Adults, Lactobacillus Acidophilus, Prebiotics and Probiotics, 60 Pills

$29.99
$25.99
 in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • ✔ 31 PROBIOTIC STRAINS: This Multi-Strain Probiotic includes clinically studied Lactobacillus acidophilus, Bifidobacterium, Saccharomyces boulardii, Lactobacillus reuteri, Lactobacillus rhamnosus, Lactobacillus gasseri, casei, Bifidobacterium longum and plantarum to help restore gut health. Contains soil based spore (SBO) like Bacillus subtilis DE111, Bacillus coagulans, and Bacillus clausii.*
  • ✔ SUPERCHARGE YOUR PREBIOTICS AND PROBIOTICS: With patented PreforPro Prebiotic Phage technology. It begins working within hours to destabilize and flush harmful bacteria like E. coli. Also contains Vegan Prebiotic Fiber Powder to boost probiotic growth as well as regularity of digestive health. SBO probiotic (spore or soil based probiotic) and prebiotic together may be part of a plan for IBS and leaky gut or SIBO treatment. *
  • ✔ THE SMART WAY TO PROTECT YOUR PROBIOTIC - TIME RELEASE! Our probiotic supplements use Stomach Acid Resistant capsules. It is a proven to guard probotics from stomach acid. NO NEED FOR REFRIGERATED STORAGE. All strains thrive at human body temps. S boulardii probiotic is the best way to keep your gut healthy for antibiotics use.*
  • ✔ PURITY, POTENCY, & QUALITY ASSURED: Gives you high potency 50 BILLION LIVE PROBIOTICS (CFU). Prebiotics and probiotics are always tested and verified by both In-House and Third-Party labs for your peace of mind. Made in USA in a cGMP Certified facility using domestic and international ingredients . ❌ DOES NOT CONTAIN eggs, fish, shellfish, peanuts, soy, sugar, GMOs, and artificial colors or flavors.
  • ✔ ENJOY OUR GUARANTEE. We stand behind all our probiotic nutritional supplements. If you are not completely satisfied with any Innovix Labs Probiotics, the risk is on us, not you! We will give you 100% money back.

Biote Medical - Multi-Strain Probiotic 20B - Practitioner-Grade Nutraceuticals - Gut + Digestive (30 Capsules)

$27.95  in stock
3 new from $27.95
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Contains 20 Billion Colonyforming Units (CFUs)
  • Supports the Gut & Digestive Health
  • Promotes a Strong Immune System
  • Soy Free, Dairy Free, Gluten Free

Renew Life Extra Care Multi-Strain Probiotic 13 Strains - 30 Billion Cultures (90 Capsules) Clinically Studied Strains (Gluten, Dairy and Soy Free) Optimal Digestive and Immune

$42.20  in stock
5 new from $37.66
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Renew Life Extra Care Multi-Strain Probiotic 13 Strains - 30 Billion Cultures (90 Capsules) Clinically Studied Strains (Gluten, Dairy and Soy Free) Optimal Digestive and Immune System
  • Helps relieve occasional constipation and maintain regularity
  • Daily support for optimal digestive and immune health
  • Quality, purity and potency are guaranteed through expiration
  • Promotes a strong healthy immune system

Douglas Laboratories Multi-Probiotic 40 Billion | Provides Probiotics and Prebiotics to Support Gut Microflora and Immunity* | 60 Vegetarian Acid-Resistant Capsules

$37.60  in stock
3 new from $36.80
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Immune Health: Offers a synbiotic blend of 16 strains that help to support immune health by balancing intestinal microflora.*
  • Shelf Stable: This formula is shelf stable and does not require refrigeration to maintain culture viability.
  • Digestive: Our digestive formulas are developed to support G.I. health and its highly complex ecosystem.*
  • Our uncompromising operational practices at our state-of-the-art manufacturing facilities surpass GMP standards and manufacturing regulations. All of our products are GMO-free.
  • For 65 years, Douglas Laboratories has been dedicated to meeting the needs of healthcare professionals. As a globally recognized leader in the development of innovative, science-based nutritional supplements, we strive to help healthcare professionals and their patients push their potential to live healthier, today and in the future.*

Kyolic Kyo-Dophilus Multi 9 Probiotic, For Strong Gut Health Balance and Support, 180 Count (Packaging May Vary)

$44.92  in stock
20 new from $43.19
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • DIVERSE MULTI-STRAIN PROBIOTIC: This multi-strain blend can help populate your microbiome with beneficial bacteria to promote strong GI health and help you maintain a balanced digestive and immune system.
  • BALANCED DIGESTIVE SUPPORT: This probiotic is specifically formulated to maintain good colon health, relieve occasional digestive discomfort, promote healthy digestive balance and general well-being.*
  • THE FRIENDLY TRIO BACTERIA: Our proprietary blend of three clinically studied strains, L. gaseri, B. bifidum and B. longum, that have been shown to be efficacious for digestive and immune health.*
  • EXPLORE WAKUNAGA: With a mission to promote good health throughout the world, Wakunaga offers nutritional supplements including Kyolic Aged Garlic products, Kyolic Specialty Items and Kyo-Green Greens & Superfoods.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

DrFormulas' Best Probiotics for Women & Men | Nexabiotic Multi Probiotic with Saccharomyces Boulardii, Lactobacillus Acidophilus, B. infantis, Prebiotic 60 Count Capsules (Not Pearls)

$29.95
$28.57
 in stock
4 new from $28.57
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • ADVANCED - Nexabiotic is DrFormulas' best 23 strain multi probiotic containing Saccharomyces boulardii, Lactobacillus acidophilus and 21 other probiotics with prebiotic.
  • EFFECTIVE - Unlike unprotected capsules that dissolve in stomach acid, Nexabiotic's vegetarian plant-based Delayed Released Capsules ensure maximum probiotic efficacy and is not just an enteric coating.
  • SMALL & STRONG - Unlike hard to swallow pearls, each tiny easy to swallow capsule has 17.25 billion CFUs at the time of manufacture to support regular bowel movements and digestive health for men and women.
  • DIVERSE - Hardy soil based probiotic organisms, Lactobacillus and Bifidobacterium species, diarrhea shortening Lactobacillus acidophilus and Saccharomyces boulardii probiotics
  • SAFE - Nexabiotic Advanced Probiotics is made in the USA in a FDA inspected GMP NSF Facility. Your safety is our priority.

Premium Probiotics for Women & Men 80 Billion CFU - Multi Strain Probiotic Supplement w/ Digestive Enzymes & Prebiotics - Mood Boosting Probiotic, Digestive & Immune Support - Non-GMO, Vegan - 30 Caps

$42.00
$24.00
 in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Complete Protection for Your Gut: With 80 billion CFU in our doctor formulated multi-strain probiotics supplement, you definitely won’t fall short of the protective benefits that the good bacteria can provide to your digestive system. What’s even more impressive? Our Probiotics Mind & Body supplement also has organic prebiotics, digestive enzymes, and Focus & Mood Support Blend to care not only for your gut but for your immunity & overall well-being too.
  • Tame Those Digestive Issues: To maintain the balance in your gut, the good bacteria need prebiotics to grow and stay alive to prevent distress in your digestive system. Our supplement contains organic prebiotic fibers and digestive enzymes to aid in digestion & nutrient absorption. These enzymes break down food particles to facilitate proper nourishment of the body. Probiotics, prebiotics & digestive enzymes come together to combat bloating, constipation & other common gut issues.
  • Balanced Gut, Better Mood: When you have discomfort in your intestines, your gut sends signals to your brain that may affect your mood. And when you’re under a lot of stress or anxious about something, it can also cause distress to your gastrointestinal system. Because we want to protect and promote this special link between your brain and gut, we added a Focus & Mood Support Blend in our capsules, making it a comprehensive supplement for your mind & body.
  • Pure Quality, Optimal Results: At Purely Optimal, our mission is to help people live longer, happier, and healthier lives. Each product is made in the USA in a GMP certified facility and is 3rd party lab tested. We stand behind our product’s safety and quality and if you’re not satisfied with the product for any reason, let us know and we’ll make it right.
  • Helping Families, Changing Lives: When children are given the chance to grow up healthy, they have the chance to dream; to live with the potential to chase every opportunity because they’re physically and mentally fit. Every purchase of a Purely Optimal product contributes to life-saving vitamins and minerals for children and mothers in need through our partnership with Vitamin Angels. By choosing Purely Optimal, you’re choosing to make a difference!

Absonutrix Probiotic Maximum Strength 50 Billion Per Capsule Multi-strain

$20.00  in stock
8 new from $20.00
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Made in USA
  • 100 Capsules
  • Proprietary Blend of multi-strains of Probiotic Bacteria

EndoMune Advanced Adult Multi-Strain Probiotic Supplement with Prebiotic | 10 Strains, 30 Billion CFU | Physician Formulated (60-Count)

$44.95  in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • HELPS WITH DIGESTIVE-RELATED SYMPTOMS – EndoMune Advanced was developed by a Gastroenterologist to support healthy gut function and may help with occasional symptoms like gas, bloating, diarrhea after taking antibiotics, and constipation.
  • ONE CAPSULE CONTAINS 30 BILLION CFUS – Unlike capsules in lower-quality supplements, our vegan capsule resists stomach acids to replenish more helpful bacteria in the intestinal tract.
  • FORMULATED BY A DOCTOR - EndoMune is a complete multi probiotic supplement containing 10 probiotic strains for optimal GI health and supporting the body's immunity. Shelf-stable vegetarian capsule with no dairy, no GMOs, no gluten, no shellfish ingredients.
  • INCLUDES PREBIOTIC FOR OPTIMAL BALANCE - Frutooligosaccharides (FOS) are included to help assist in maintaining the vitality and growth of helpful Bifidobacteria and Lactobacilli strains.
  • CONTAINS Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus casei, Streptococcus thermophilus, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactococcus lactis, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium longum.

Douglas Laboratories Multi-Probiotic 15 Billion | Multi-Strain Shelf Stable Probiotic with Prebiotic FOS | 60 Vegetarian Acid-Resistant Capsules

$43.30  in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Gastrointestinal Support: Each capsule contains over 15 billion beneficial organisms for immune health and gastrointestinal support.*
  • Shelf Stable: This formula is shelf stable and does not require refrigeration to maintain culture viability.
  • Digestive: Our digestive formulas are developed to support G.I. health and its highly complex ecosystem.*
  • Our uncompromising operational practices at our state-of-the-art manufacturing facilities surpass GMP standards and manufacturing regulations. All of our products are GMO-free.
  • For 65 years, Douglas Laboratories has been dedicated to meeting the needs of healthcare professionals. As a globally recognized leader in the development of innovative, science-based nutritional supplements, we strive to help healthcare professionals and their patients push their potential to live healthier, today and in the future.*

Pharmax - HLC Multi Strain - Probiotic Supplement to Support Gut Flora - 60 Capsules

$47.50  in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Gastrointestinal Support: Multistrain probiotic formula, including four tested strains promotes gastrointestinal health*. Probiotics also reinforce the epithelial barrier, and they control permeability by mediating tight junction integrity.*
  • Refrigerate: This formula requires refrigeration to maintain culture viability.
  • 15 Billion CFU Per Capsule: Provides 16 probiotic strains and 15 billion CFU per capsule. HLC Multi Strain is a 15 billion CFU probiotic formula, providing four strains of proprietary, human-sourced Lactobacillus acidophilus, Bifidobacterium bifidum and Bifidobacterium animalis subsp.

Multi-Strain Support Probiotics Capsules, Digestive Advantage Ultra 20 (24 Count In A Box) - Supports Digestive and Immune Health (Packaging May Vary)

$23.20  in stock
3 new from $15.39
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • MULTI-STRAIN PROBIOTIC: A unique 4-strain blend of probiotics with 10 billion CFUs per capsule.
  • HELPS TO RELIEVE: Occasional diarrhea, minor abdominal discomfort and occasional bloating.
  • INGREDIENTS ARE: Non-GMO, Dairy Free and Vegetarian
  • CLINICALLY PROVEN PROBIOTIC BLEND: That helps restore digestive balance.
  • SCHIFF QUALITY GUARANTEE: This probiotic is tested and meets our high standards for purity, freshness and potency (labeled potency of live cultures).

Dr. Drew Sinatra’s LifeBiome Gut Restore Advanced, Maximum Strength Microbiome Probiotic with Fermented Botanicals, 11 Multi Strains, 30 Once-Daily Capsules, Vegetarian, Soy-, Dairy-, and Gluten Free

$44.99  in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • ADVANCED STRENGTH MICROBIOME PROBIOTIC WITH 11 DIVERSE STRAINS IN A BLEND OF 13 BILLION LIVE PROBIOTICS. Supports your variety of gut flora with the best lactobacillus and bifidobacteria strains, beneficial yeast- and soil-based probiotics, and fermented botanicals. A variety of strains is key to great gut health, not megabillions of just a few strains.
  • MAXIMUM STRENGTH SUPPORT FOR LESS DIGESTIVE UPSET AND MORE DIGESTIVE COMFORT, A BOOSTED MOOD, AND OVERALL QUALITY OF LIFE. Features one of the top clinically validated soil-based organism (SBO) strains, B. coagulans LactoSpore, which has been shown to improve gas, bowel movements, and constipation, plus improve mental health, mood, daytime drowsiness, and skin health in adults with abdominal concerns.
  • PROBIOTICS ARRIVE ALIVE TO YOUR GUT USING SMART-RELEASE TECHNOLOGY AND ARE GUARANTEED AT EXPIRATION AS LISTED ON THE BOTTLE. The number of live organisms on the bottle is what’s alive in your bottle even on the last day of expiration. Live probiotics get delivered to your intestines using SMART-Release technology.
  • EASY-TO-SWALLOW, PLANT-BASED, VEGETARIAN CAPSULES. MADE IN THE USA with ingredients sourced from around the world. “Green and clean” formula without artificial sweeteners, preservatives, and colors, free of gluten, dairy, and soy and made without shellfish, fish, tree nuts, peanuts, and eggs.
  • FORMULATED BY BOARD-CERTIFIED, PRACTICING NATUROPATHIC DOCTOR DREW SINATRA, one of the leaders of America’s new generation of “green medicine” practitioners. He is the son of integrative cardiologist and heart health expert Dr. Stephen Sinatra. Backed by a 100% satisfaction guarantee.

DrFormulas Chewable Probiotics for Kids & Adults | for Oral Dental Health, Bad Breath, Better Digestion 20 Multi Strain - S boulardii, Lactobacillus plantarum and Bifidobacterium infantis, 60 Chews

$19.58  in stock
2 new from $19.58
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • PACKED WITH PROBIOTICS: Each chewable probiotic tablet is loaded with 20 different probiotic strains to support oral and gut health.
  • UNIQUE FORMULA: Our probiotic for kids and adults contain high quality probiotics such as Saccharomyces boulardii, Bifidobacterium infantis, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus helveticus, and Bifidobacterium breve
  • STOMACH ACID RESISTANT PROBIOTICS: DrFormulas Chewable Probiotics are easy to swallow and utilizes stomach-acid resistant probiotics that can survive the passage through harsh stomach acid
  • STRONG BUT GENTLE: Powerful probiotics strong enough for adults and gentle enough for kids provide oral and gut health support. Gluten and gelatin free.
  • MADE IN THE USA: All of our supplements are made in a NSF inspected Good Manufacturing Practices facility. Your safety is our top priority.

Jarrow Formulas Jarro-Dophilus EPS - 5 Billion Viable Organisms Per Serving - 60 Enteric Coated Veggie Caps - Multi-Strain Probiotic - Intestinal & Immune Health - Up to 60 Servings

$18.87
$17.22
 in stock
3 new from $17.22
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Multi-Strain - Jarro-Dophilus EPS is a shelf-stable, multi-strain probiotic formulated with clinically documented strains. Supports health of the entire intestinal tract with 8 probiotic species from 6 different genera, including B. longum BB536.*
  • Intestinal & Immune Health - Each strain in Jarro-Dophilus EPS has been clinically validated by scientific research and assigned a strain designation that links to the positive influence on intestinal and immune health.*
  • 5 Billion CFU - Delivers a minimum of 5 billion viable cells at time of consumption (when kept under recommended storage conditions and used within Best Used Before date). No refrigeration necessary.
  • Enhanced Probiotic System - Formula includes EnteroGuard coating to protect against stomach acid & blister packing defense against air and moisture. Ensures probiotic strains are delivered to the intestinal tract to fully exert their benefits.
  • Rated #1 - With innovative, science-based probiotic products that consumers trust, Jarrow Formulas has again been recognized as the #1 probiotic brand for customer satisfaction according to ConsumerLab’s Survey of Supplement Users for 2021.

Jarrow Formulas Jarro-Dophilus EPS - 5 Billion Viable Organisms Per Serving - 120 Enteric Coated Veggie Caps - Multi-Strain Probiotic - Intestinal & Immune Health - Up to 120 Servings

$40.95
$30.00
 in stock
5 new from $29.98
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • Multi-Strain - Jarro-Dophilus EPS is a shelf-stable, multi-strain probiotic formulated with clinically documented strains. Supports health of the entire intestinal tract with 8 probiotic species from 6 different genera, including B. longum BB536.*
  • Intestinal & Immune Health - Each strain in Jarro-Dophilus EPS has been clinically validated by scientific research and assigned a strain designation that links to the positive influence on intestinal and immune health.*
  • 5 Billion CFU - Delivers a minimum of 5 billion viable cells at time of consumption (when kept under recommended storage conditions and used within Best Used Before date). No refrigeration necessary.
  • Enhanced Probiotic System - Formula includes EnteroGuard coating to protect against stomach acid & blister packing defense against air and moisture. Ensures probiotic strains are delivered to the intestinal tract to fully exert their benefits.
  • Rated #1 - With innovative, science-based probiotic products that consumers trust, Jarrow Formulas has again been recognized as the #1 probiotic brand for customer satisfaction according to ConsumerLab’s Survey of Supplement Users for 2021.

Daily Multi-Strain Probiotic Gummies for Digestive Health & Gut Health, Digestive Advantage Ultra Probiotics for Men and Women (65 Count Bottle) - Natural Fruit Flavor

$26.99  in stock
3 new from $26.99
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • MULTI-STRAIN PROBIOTIC GUMMIES FOR MEN & WOMEN: These delicious probiotic gummies help lessen minor abdominal discomfort & occasional bloating.* 4X the CFUs!
  • CLINICALLY TESTED PROBIOTIC STRAIN: BC30 is protected by a natural protein shell to help it survive stomach acid 100X better.§ This survivability means more can reach your gut, where it can help support digestive & immune health.*
  • DIGESTIVE HEALTH + IMMUNE SUPPORT: Did you know that 70% of your immune system is located in your digestive tract? That’s where our patented BC30 probiotic can interact with intestinal cells to help support your body’s overall digestive & immune health.
  • #1 PROBIOTIC GUMMY BRAND1: Digestive Advantage is the #1 Probiotic Gummy brand. Don’t take our word for it, check out our 12k+ ratings and read our customer reviews.
  • GREAT TASTE & TRUSTWORTHY INGREDIENTS: These delicious gummies are a convenient and easy choice for adults. Digestive Advantage products are guaranteed for freshness, purity, and labeled potency.

Intestine

$0.99  in stock
Amazon.com
as of March 1, 2022 7:30 pm

Features

Is Adult Product
Release Date2018-11-29T01:27:30.158Z
LanguageEnglish

NewRhythm Probiotics 50 Billion CFU 20 Strains, 60 Veggie Capsules, Targeted Release Technology, Stomach Acid Resistant, No Need for Refrigeration, Non-GMO, Gluten Free

$27.99
$16.99
 in stock
5 new from $16.99
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • ★Made in New York, USA★ NewRhythm 50 Billion Probiotics is made in a Facility Based in New York, USA. Our Facility is GMP Certificated, which Represent the Highest Level of Technology, Quality Purity and Consistency.
  • ★50 Billion 20 Strains Targeted Release Formula★ NewRhythm 50 Billion Probiotics Capsules is Scientifically Backed and Clinically Proven, Formulated by Doctor with 50 Billion Living Organisms Per Serving, Featuring Targeted Release Technology to Help Probiotics Survive Stomach Acids and Reach Your Intestinal Track. Organic Prebiotics Fiber is also Included In the Formula.
  • ★Potent and Pure for Your Digestive Health and Immune Health*★ Our All Natural Probiotics Provides Support For the Establishment and Maintenance of Favorable Intestinal Flora. Gives You Powerful Support for Healthy Digestion and Balanced Intestinal Ecology. Our Products are Shelf Stable that Does NOT Require Refrigeration.
  • ★100% Natural, Non-GMO, Gluten Free★ NewRhythm 50 Billion Probiotics is Formulated with 100% Natural Ingredients and Independently Tested in 3rd Party Labs in USA. Our Probiotics Supplement is Verified NON-GMO, Gluten Free and Verified Free of Sugar, Soy, Yeast, Egg, Wheat, Corn, Peanuts, Fish, Shellfish, Magnesium Stearate, Artificial Ingredients, Fillers, Binders, Preservatives.
  • ★100% Satisfaction Guaranteed★ We stand behind our products with confidence. If in anyway you are not completely satisfied with our products, please let us know in 30 days, we will give you money back.

NOW Supplements, Probiotic-10, 25 Billion, with 10 Probiotic Strains, Dairy, Soy and Gluten Free, Strain Verified, 100 Veg Capsules

$49.99
$26.01
 in stock
11 new from $26.01
Free shipping
Amazon.com
as of March 1, 2022 7:30 pm

Features

  • 10 PROBIOTIC STRAINS: Offers a balanced spectrum of live organisms consisting of acid-resistant probiotic bacterial strains that are known to naturally colonize the human GI tract*
  • CLINICALLY VALIDATED STRAINS*: Utilizes bacterial strains that have been clinically validated for their support of healthy immune system function*
  • HEALTHY INTESTINAL FLORA*: Probiotic bacteria are critical for healthy digestion, helping maintain the integrity of the intestinal lining, support proper intestinal motility, and participate in the detoxification process*
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
  • Packaged in the USA by a family owned and operated company since 1968

Best Multi Strain Probiotics 2022 | Price Comparison

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